The early 17th century saw further rebuilding. Sir Martyn Grene and the Coppin family who followed, had, by 1613, refurbished the orchards, fish pond and dovecote, and rebuilt the south wing. 

By 1634 the Manor had been purchased by Thomas, Lord Coventry, trusted servant of James I. He became lord keeper of the Great Seal, one of the most important ministerial positions in the land. When Charles I ascended to the throne, Milton was one of Lord Coventry’s favourite retreats and it may have been he who removed the old service block on the north side of the hall and built the staircase.

A new entrance from the road, with ornamental gateway was aligned with the porch and the old gatehouse was removed. The Coventry family owned the Manor until 1773.

In 1908 the house was greatly enlarged. Where possible, local stone was used and most of the windows were replaced and darker north Oxfordshire stone was used for the new housing. A large south wing was added as well as a new more impressive drive and gateway, built in line with the old south wing, which became the new porch.

It seems fitting that the last private owner of Great Milton Manor should Hon. David Bewicke-Copley, who, after he succeeded his father as Lord Cromwell in 1966, became Senior Government Broker.